Lindsey Morgan-I love her work on The CW show The 100. Her character Raven has that toughness and vulnerability which she wears so well. It's something I see in my "first" protagonist, werewolf Rhea Ortiz.
Ryan Reynolds-In my humble opinion, he can be serious and funny when he pulls it out. His role on Blade: Trinity was a slight influence on my male protagonist. I think Reynolds can do the cop role when it calls for it.
Ciara Renee-For the role of college coed/superheroine, I think of Ciara Renee. Her portrayal of Hawkgirl in The Flash, Arrow, and DC's Legends of Tomorrow is good. The whole "coming-into-your-own" character is the central concept for my superhero comic I have in mind for everyone including young girls and Renee pulls it off.
And that's my dream casting for my characters coming to life on TV or movies.